Brazil Confirms 22,831 Zika Cases

Since the Zika virus disease was first detected in the Americas in May 2015, over 50 countries and territories in the region have reported cases transmitted by mosquitoes.

Unfortunately, the Federative Republic of Brazil has historically led in the number of cases.

As of November 13, 2025, the Pan American Health Organization (PAHO) reported Brazil has confirmed 22,831 cases of Zika this year alone. Many of these cases are found in the city of Rio de Janeiro, which is home to over 6 million people.

The other countries with the highest case numbers in 2025 include Bolivia, with 1,024 cases, and Argentina, with 892 cases.

Additionally, near the southern border of the United States, Mexico has reported three cases of Zika in 2025, down from 30 cases reported last year.

The PAHO writes, 'While efforts are underway to improve the sensitivity of surveillance systems, a lack of detection is no guarantee that the Zika virus is not circulating or that local transmission has been interrupted.'

Currently, the U.S. CDC reports no geographic areas with an active Zika Travel Health Notice.

The PAHO and the CDC discourage pregnant women from visiting Zika-endemic areas.

From a disease-prevention perspective, one innovative Zika vaccine (VLA1601) is progressing through clinical trials in 2025.