Travel Vaccine Breaking News

Travel vaccine breaking news brought to you by Vax Before Travel.

Jul 3, 2025 • 3:03 pm CDT
JAMA Network Open 2025

A new study, published this week in JAMA Network Open and conducted by researchers from the University of Kentucky, analyzed data from the Cancer Statistics Incidence Analytic Database.

Released on June 30, 2025, this study's findings underscore the significant burden of cancer linked to human papillomavirus (HPV) among residents of Appalachia, who have a 16% higher rate of HPV-related cancers.

Furthermore, regional-specific disparities were seen for HPV-associated male and female oropharyngeal cancers, female anal cancer, vulvar cancer, cervical cancer, and penile cancer.

Incidence was highest among individuals living in the North Central and Central regions.

The North Central subregion had the highest incidence rates of male oropharyngeal cancer.

In contrast, the Central and North Central subregions had significantly higher rates of vulvar, cervical, and penile cancers than the other subregions.

These researchers wrote, 'This cross-sectional study of HPV-associated cancer incidence found disproportionately high HPV-associated cancer rates among Appalachian residents compared with non-Appalachian residents.'

'These findings highlight the need for targeted efforts to improve HPV vaccine uptake and encourage adherence to evidence-based screening guidelines for HPV-associated cancers in Appalachia.'

Currently, the U.S. CDC recommends HPV vaccination for most adolescents in a two or three-dose regimen. And recommends vaccination for everyone through age 26 if not adequately vaccinated at a younger age.

As of July 3, 2025, Merck's Gardasil 9 vaccine is readily available at health clinics and pharmacies throughout the Appalachian Mountain range and the United States.

Jul 3, 2025 • 2:41 pm CDT
TDSHS 2024

Following a significant outbreak in 2024, the first confirmed case of West Nile virus illness was reported on June 24, 2025, in a resident of Brazos County, Texas.

This Texas Department of State Health Services (DSHS) announcement raises concerns for all Texans as virus-carrying mosquitoes remain active into December.

There were 455 cases of West Nile disease in Texas in 2024 and 56 related fatalities.

Over the last five years, Texas has had 929 West Nile cases and 122 deaths.

“Texans should be aware that mosquitoes transmit disease, and some of these illnesses, like West Nile and dengue, can be severe,” said DSHS  Commissioner Jennifer A. Shuford, MD, MPH. “But taking steps to prevent mosquito bites and eliminating mosquito breeding areas around homes are proactive measures that can reduce the risk of mosquito-borne illness.”

Infected mosquitoes transmit West Nile virus after biting. Although 80% of people exposed to the virus do not develop symptoms, the remaining 20% will experience symptoms such as fever, nausea, headache, fatigue, and muscle and joint pain.

Less than one percent of those exposed will suffer from West Nile neuroinvasive disease, which affects the nervous system and can cause disorientation, neck stiffness, tremors, paralysis, convulsions, and even death.

DSHS urges anyone experiencing West Nile symptoms to contact their health care provider and mention any exposure to mosquitoes.

As of July 3, 2025, no vaccine for West Nile virus exists.

Jul 2, 2025 • 1:40 pm CDT
Florida Dept Health June 2025

Florida health officials recently reported additional cases of mosquito-transmitted and travel-related chikungunya, dengue, and malaria in 2025.

After a slow start, these serious diseases have been concentrated in southeast Florida, in the great Miami area, which welcomes millions of international visitors each year.

Currently, Miami-Dade County remains under a mosquito-borne illness alert.

As of June 28, 2025, Florida Health's Weekly Arbovirus Report confirmed a second, indigenous case of dengue in Miami-Dade County.

The most recent case has been identified as serotype DENV-4, while the early case was DENV-3.

In 2024, a total of 91 cases of locally acquired dengue have been reported across ten Florida counties.

Additionally, there have been four cases of chikungunya and 20 cases of malaria related to international travelers this year.

While there are no travel advisories issued for Florida's southeast coast, Canada and the UK both advise speaking with a travel vaccine expert before visiting at-risk areas in 2025.

Jul 2, 2025 • 6:44 am CDT
Google Maps July 2, 2025

The regional health agency in Grand Est, France, reported its first locally acquired case of chikungunya in Bas-Rhin.

As of July 1, 2025, epidemiological investigations indicated that this locally acquired chikungunya case had frequented the municipalities of Lipsheim and Fegersheim during their infectious period. 

Unlike previous local cases, this area is located in France's northeast.

In June 2025, Occitane (Hérault and Gard), Provence-Alpes-Côte d'Azur (Var and Bouches-du-Rhône), Auvergne-Rhône-Alpes (Drôme), and the island of Corse (Corse-du-Sud) reported local chikungunya cases.

And in the southern Indian Ocean, France's departments have reported significant chikungunya outbreaks in 2025.

According to the World Health Organization and the United States, chikungunya is a vaccine-preventable disease, with two vaccines commercially available as of July 2025. 

 

Jul 2, 2025 • 5:42 am CDT
Micron Biomedical 2025

Emory University and Micron Biomedical recently announced the first clinical trial for a novel rotavirus vaccine, CC24.

This vaccine candidate is delivered using dissolvable microarray technology and is currently enrolling participants in the Phase 1 study, which launched in mid-June 2025.

Notably, this trial represents the first clinical evaluation of a drug or vaccine administered via patch or microarray, sponsored by the U.S. Centers for Disease Control and Prevention (CDC).

"CDC recognizes the potential of this groundbreaking clinical trial, which will test the safety of both our novel vaccine, CC24, in adults and the vaccine's delivery with 'patch' technology," says Dr. Demetre Daskalakis, Director of CDC's National Center for Immunization and Respiratory Diseases, in a press release.

"The trial marks significant progress in vaccine technology innovation and is a critical step toward saving more children from rotavirus illness and death." 

Rotavirus infection is a leading cause of diarrheal deaths among children, particularly in low and middle-income countries where existing oral vaccines are often less effective. CC24 is a uniquely inactivated rotavirus vaccine developed by the CDC to provide an alternative to the oral administration of rotavirus vaccines.

Micron Biomedical's unique needle-free technology rapidly delivers vaccines and therapeutics via dissolvable microarray compounds that are painlessly pressed into the upper layers of the skin. 

As of July 2, 2025, U.S.-FDA-approved rotavirus vaccines are available.

Jul 1, 2025 • 2:38 pm CDT
US State Dept July 2025

According to the Secretary of State at the Ministry of Foreign Affairs and International Cooperation, Honduran authorities are requiring documentation to show proof of a measles vaccine (MMR) for travelers coming from various countries, including the United States.

As of June 28, 2025, this new requirement applies to all foreign travel to the Republic of Honduras, whether by land, sea, or air. 

The U.S. Embassy in Honduras stated that if someone cannot receive the vaccine, they will need to provide proof of a negative measles test result 72 to 80 hours before the flight.

This means that cruise ship passengers visiting this Central American country may need to carry proof of their vaccination.

In addition to measles vaccination, the U.S. CDC recommends being protected against chikungunya, dengue, malaria, typhoid, and Zika when visiting Honduras.

For local assistance during July 2025, the U.S. Embassy Tegucigalpa is available to U.S tourists.

Additionally, the Department of State stated in 2024, "Reconsider travel to Honduras due to civil unrest." The Smart Traveler Enrollment Program is available to travelers interested in receiving digital travel alerts while abroad.

Jul 1, 2025 • 12:06 pm CDT
Maps July 1, 2025

In June 2025, the WHO's Dengue Situation Update #723 confirmed that the Western Pacific Region continues to face a high burden of mosquito-borne arboviral diseases, particularly Dengue. 

Within the Philippines, Quezon City (QC) declared a Dengue outbreak in February 2025

The QC government today published updated data regarding the ongoing outbreak.

The QC Epidemiology and Surveillance Division (QCESD) dashboard reported on July 1, 2025, that 5,762 dengue cases were reported in 2025, with QC's District 2 confirming the highest number of cases.

The QCESD stated that most fatal dengue cases (23) involved children and young women.

To alert international travelers visiting QC, a metro area with about 3 million residents located north of Manila, the U.S. Centers for Disease Control and Prevention included the Philippines in its Global Dengue Outbreak Advisory issued in June 2025.

Without a preventive vaccine available in the U.S., the CDC recommends that travelers to risk areas should prevent mosquito bites by using an EPA-registered insect repellent, wearing long-sleeved shirts and long pants when outdoors, and sleeping in an air-conditioned room or one with window screens.

Jun 30, 2025 • 4:10 pm CDT
US CDC June 2025

Like many countries in South America, the Plurinational State of Bolivia has been confronted with a multi-year outbreak of Chikungunya.

To alert international travelers visiting Bolivia, the U.S. Centers for Disease Control and Prevention (CDC) issued a Level 2 Travel Health Advisory on June 26, 2025, stating that this year's Chikungunya outbreak is centered in Bolivia's Santa Cruz department.

According to recent data, Bolivia welcomed around 984,000 international tourists in 2024.

Data released at the end of June 2025 indicates Bolivia has reported 3,863 Chikungunya cases this year and 505 cases in 2024.

So far in 2025, about 38 people have returned to the U.S. infected with the Chikungunya virus.

The CDC advises that if you are pregnant, you should reconsider travel to the affected areas, especially if you are nearing the time of delivery. Mothers infected around the time of delivery can pass the virus to their baby before or during delivery.

Newborns infected in this way or by a mosquito bite are at risk for severe illness, including poor long-term outcomes.

Furthermore, vaccination is recommended for most travelers who are visiting an area with a Chikungunya outbreak.

As of June 30, 2025, Chikungunya vaccines are approved for use by the CDC and are commercially available at travel clinics and pharmacies in the United States.

Jun 30, 2025 • 1:39 pm CDT
Evaxion A/S 2025

Current polio vaccines are made from either inactivated or weakened versions of the virus. These vaccines have been administered worldwide for many decades.

However, this approach presents challenges in certain situations. It highlights the need for an improved vaccine that does not rely on the virus itself, particularly as the global community strives to end poliovirus infections.

As of June 30, 2025, the U.S. Centers for Disease Control and Prevention identified poliovirus detections in 41 countries.

Developing vaccine formulations that do not use live viruses in their production would be highly beneficial, as it would eliminate the potential safety risks associated with handling and growing the virus, wrote Evaxion A/S in early June 2025.

To address this need, Evaxion received undisclosed funding from the Gates Foundation to help eradicate polio worldwide by exploring design options for a new and innovative vaccine.

This project will combine Evaxion’s leading and clinically validated AI-Immunology™ platform to identify and combine various antigens to combat the virus. Based on these findings, several new antigen constructs will be designed for selection and validation.

“We are thrilled to receive support from the Gates Foundation and help the world achieve the goal of completely eradicating polio. We are excited to apply our AI-Immunology™ platform to combat yet another infectious disease. The grant allows for further application and validation of our platform without adding to our operational spend,” says Christian Kanstrup, CEO of Evaxion, in a press release on June 3, 2025.

The inactivated (killed) polio vaccine (IPV) was developed in 1955 to produce antibodies in the blood that target all three poliovirus types, thereby preventing the spread of the virus, and has been offered in the U.S. since 2000.

IPV vaccinations are offered at clinics and pharmacies in the U.S.

Jun 30, 2025 • 1:12 pm CDT
Maps June 30, 2025

Rabies has been present in the wildlife population in New Jersey since 1989, affecting the entire state.

Rabies is a virus that can affect any mammal, including cats, dogs, raccoons, skunks, and bats, the unfortunate source of most rabies cases in the United States.

In NJ, groundhogs have been a significant source of rabies.

Recently, the Hillsborough Health Department tested a groundhog that bit two people outside of a business at The Landing business complex. This animal tested positive for rabies. 

As of June 27, 2205, rabies vaccinations of all cats and dogs, with few exceptions, are required in Hillsborough Township.

The virus lives in the central nervous system fluid and saliva of the affected animal. This infectious fluid must enter the host’s body thost's an opening put there by a bite, or a scratch, or through exposure of an open cut, or rubbing the eyes after touching saliva.

'If any anima' bites you, wash the wound immediately with soap and water and seek medical attention,' says the NJ Hea'th Department.

Additionally, rabies vaccination is immediately recommended for people bitten by a rabid animal.

 

 

Jun 28, 2025 • 2:08 pm CDT
Maps June 28, 2025

Since 1952, when the first Japanese Encephalitis (JE) case in India, this mosquito-transmitted disease has been a significant public health concern.

Local media reported in late June 2025 that an outbreak of JE is responsible for 32 people being admitted to a hospital, with four related fatalities, in Assam, a state in northeastern India.

Since April 2025, the Japanese Encephalitis virus (JEV) has primarily affected areas with pig-rearing and paddy field activity, both known risk zones for virus transmission by infected mosquitoes.

These mosquitoes acquired the JEV from pigs, birds, and sheep.

According to data from the Integrated Disease Surveillance Programme, about 925 JE cases were detected in Assam in 2024.

To help reduce the impact of this severe disease, JE vaccinations have been started in Assam's nine districts.

Assam is located south of the eastern Himalayas along the Brahmaputra and Barak River valleys, just to the east of Nepal, where twenty-nine districts have reported JE cases.

To alert international travelers visiting Assam and Nepal, the U.S. CDC recommends vaccination for travelers who are moving to an area with an outbreak or spend extended periods in areas with Japanese encephalitis cases.

When departing from the United States, an approved JE vaccine (IXIARO®) is commercially offered at travel clinics and pharmacies.

Jun 28, 2025 • 4:17 am CDT
US CDC June 2025

The World Health Organization (WHO) has published the 54th situation report for the multi-country outbreak of mpox, which began in May 2022.

The WHO Director-General recently confirmed that the ongoing upsurge of mpox cases continues to constitute a public health emergency of international concern.

On June 27, 2025, the WHO confirmed that during May 2025, a total of 6,823 confirmed mpox cases and 16 deaths (Case Fatality Ratio: 0.2%) were reported. The majority of mpox instances continue to be reported from the WHO African Region, with 18 countries currently experiencing active ongoing transmission.

Since the last WHO report, Ethiopia and Italy have reported their first cases of mpox, caused by the clade Ib monkeypox virus (MPXV).

In addition, North Macedonia, the Republic of the Congo, and Togo have reported their first cases of mpox clade IIb MPXV. Albania has reported its first mpox case.

According to a disease prevention update, the WHO reported that seven African countries have initiated mpox vaccination. More than 731,000 doses of the MVA-BN (JYNNEOS) vaccine have been administered to date.

In the United States, there have been four reported cases of clade I mpox in people who had recently traveled to affected areas in Central and Eastern Africa. 

The U.S. CDC advises that when visiting countries in Africa, such as the Democratic Republic of the Congo, you should get your first mpox vaccine at least 6 weeks before traveling, if possible. After completing your first and second vaccine doses, which are given four weeks apart, it takes about two more weeks to achieve the best protection against mpox.

Whether or not you've been vaccinated, continue to reduce your risk of getting mpox, says the CDC.

Jun 27, 2025 • 8:04 am CDT
UK FCDO June 2025

Recently, the UK Foreign, Commonwealth and Development Office (FCDO) advised against all travel to several volcanoes in the Republic of Indonesia. 

On June 18, 2025, the FCDO stated that ash plumes from volcanoes can have a significant impact on health, particularly for individuals with pre-existing respiratory conditions, such as asthma.

Additionally, during the dry season from May to November, widespread wildfires cause a smoke haze that drifts across parts of Indonesia, particularly the Riau Islands, central Sumatra, and Kalimantan.

The haze can disrupt local and regional air travel, and air pollution has a significant impact on public health. 

If you plan to visit Indonesia in 2025, the UK advises researching your destinations and obtaining suitable travel insurance. Insurance should cover your itinerary, planned activities, and expenses in the event of an emergency.

Seperately, the U.S. Department of State recently issued a level 4 advisory for international visitors to consider before visiting Indonesia.

From a health perspective, the U.S. CDC includes Indonesia in recent measles and polio travel advisories.

As of June 2025, Indonesia's dengue cases had risen to 52,410, with 210 deaths reported this year. And chikungunya cases reached 1,245, primarily in Java.

The CDC suggests speaking with a travel vaccine expert before visiting Indonesia this year.

Jun 27, 2025 • 6:25 am CDT
Pixabay 2025

With the continued confirmations of mpox infections in various countries, the U.S. FDA-approved vaccine is now being evaluated for at-risk, vulnerable populations.

Bavarian Nordic A/S announced that on June 26, 2025, the initiation of the first of two clinical trials designed to support approval and use of the MVA-BN® (JYNNEOS) mpox/smallpox vaccine in infants under 2 years of age, pregnant, and breastfeeding women.

Both studies are conducted in the Democratic Republic of Congo, the epicentre of the ongoing mpox outbreak in Africa, where infants and pregnant women remain highly vulnerable to the sexually transmitted mpox virus.

Paul Chaplin, President & CEO of Bavarian Nordic, commented in a press release, “These new studies will fill the gap by providing important data about the use of MVA-BN ... which could help support a label expansion for MVA-BN to include the most vulnerable populations.”

Furthermore, these studies are part of the PregInPoxVac research project, which includes a phase 2 trial of MVA-BN in children aged 2-11 years. Topline results from this trial (NCT06549530) are anticipated in the third quarter of 2025.

Currently, JYNNEOS is commercially offered in the United States at various clinics and pharmacies.

According to the U.S. CDC, the majority of clade II mpox cases in the U.S. continue to be in people who are not vaccinated or who have received only one dose of JYNNEOS.

As of June 1, 2025, approximately 35,000 mpox infections had been reported in the United States.

Jun 27, 2025 • 5:54 am CDT
Google Maps 2025

The mosquito-transmitted West Nile virus (WNV) has been actively spreading throughout 14 Louisiana parishes since 2002 and continues to do so in 2025.

On June 25, 2025, the Louisiana Department of Health (LDH) confirmed Louisiana’s first human case of WNV of the 2025 mosquito season. This case was confirmed in an individual from Livingston Parish, located east of Baton Rouge and north of New Orleans, who was hospitalized due to complications from the infection.

In 2024, there were 57 confirmed human cases of WNV in Louisiana, including three deaths. 

In 2024, 1,466 WNV cases were confirmed in 49 states in the USA, led by Texas with 176 cases.

The LDH says WNV can cause mild to severe illnesses. While most people infected with West Nile virus develop no symptoms, about 20% of infected individuals develop West Nile fever, a flu-like illness characterized by symptoms that can include fever, headaches, body aches, nausea, and rashes. About 1 in 150 people who are infected with WNV develop a severe illness that can affect the brain, spinal cord, and nerves, which may even cause paralysis or death.

WNV is an international concern.

For example, according to a research program by the UK Health Security Agency and the Animal and Plant Health Agency, WNV genetic material was detected in mosquitoes in Britain for the first time in 2025.

As of June 27, 2025, vaccine candidates to protect people against WNV have not been approved in the United States.