Three Countries Confirm 303 Zika Cases in 2025

The Pan American Health Organization (PAHO) has confirmed local transmission of the Zika virus in countries and territories in the Region of the Americas for several years.

As of February 1, 2025, 303 Zika cases were reported in the Americas this year, with cases reported in Brazil, Bolivia, and Colombia. 

Last year, the PAHO reported a 13% increase in cases.

Over 42,127 ZIka cases and two related fatalities in the Americas in 2024.

In 2024, very few cases were reported in the United States. The CDC's preliminary data show 19 travel-related cases and nine locally acquired cases in U.S. territories, such as Puerto Rico.

While the CDC does not recommend any Zika vaccine candidate, Valneva SE's VLA1601 second-generation purified, inactivated, whole Zika virus vaccine candidate is the most advanced Zika vaccine in development. However, this innovative vaccine will probably not be commercially available in 2025.