Angola Leads Africa's Cholera Outbreak in September 2025

During 2025, various African countries have reported outbreaks of cholera, which have killed tens of thousands of people.

This vaccine-preventable and treatable disease is caused by drinking water or eating food contaminated with cholera bacteria, such as raw shellfish.

According to the Africa Centers for Disease Control and Prevention (ACDC) Epidemic Intelligence Weekly Report, since the beginning of 2025, over 75,000 cholera cases and 490 deaths (CFR: 0.66%) have been reported across 22 African Union Member States this year.

Specifically, the Republic of Angola has been the most impacted country this year.

The ACDC reported on September 15, 2025, that between January and early September, a total of 28,102 cases of cholera had been reported from 18 of the 21 Angolan provinces.

Most upsetting, there has been a 46% average increase in the number of new cases reported in the last four weeks.

The U.S. CDC recommends that if you're traveling to an area where cholera is present, or where the water and food are unsafe to drink and eat, follow these five prevention measures: visit a doctor or travel clinic/pharmacy to discuss cholera vaccination options. 

In addition to cholera vaccination, the CDC recommends travel vaccines to protect travelers from measles and polio outbreaks in Angola, which is located on Africa's southwest coast.