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Aug 23, 2025 • 11:45 am CDT
Health Canada August 2025

While there is a global alert issued regarding measles outbreaks, Canada is unfortunately the leader in the Region of the Americas.

As of mid-August 2025, over 4,638 measles cases have been reported to Health Canada.

According to the Pan American Health Organization (PAHO) weekly update, Canada's national trends show that transmission is persisting, particularly in Alberta, British Columbia, Manitoba, and Ontario, following an outbreak that began in New Brunswick in October 2024.

"Measles is preventable with two doses of a vaccine, which is proven to be very safe and effective. To stop these outbreaks, countries must urgently strengthen routine immunization and conduct targeted vaccination campaigns in high-risk communities," said Dr. Daniel Salas, Executive Manager of the Special Program for Comprehensive Immunization at PAHO, in a media release on August 15, 2025.

Following Canada, Mexico has reported over 3,911 measles cases this year.

Located between these countries, the State of Texas recently declared its extensive measles outbreak over.

To alert international travelers of this very contagious virus, the U.S. CDC includes Canada in its Travel Health Advisory.

The CDC recommends travelers be fully immunized against measles before traveling abroad in 2025.

 

Aug 23, 2025 • 5:46 am CDT
Google Maps 2025

A portion of Santa Clara County has been placed under quarantine for the Mediterranean fruit fly (Medfly) following the detection of two wild female flies in the city of San José.

According to a media release by the California Department of Food and Agriculture Office of Public Affairs (CDFA) on August 21, 2025, if not stopped, Medflies can devastate fruits and vegetables by reproducing and leaving larvae in produce.

The quarantine area measures approximately 109 square miles, bordered on the north by Trade Zone Boulevard; on the south by Camden Avenue; on the west by San Tomas Expressway; and on the east by Evergreen Valley Community College. 

The quarantine will cover parts of the cities of San José, Santa Clara, Campbell, and the town of Los Gatos. A link to the quarantine map may be found here: www.cdfa.ca.gov/plant/medfly/regulation.html.

Sterile male Medflies are scheduled to be released in the area as part of the eradication effort. The release rate will be 250,000 males per square mile per week in an 84.76 square mile area around the infestation. 

Sterile male flies mate with fertile wild female flies in the natural environment but produce no offspring. The fly population decreases as the wild flies reach the end of their natural life span with no offspring to replace them, ultimately resulting in the eradication of the pest.

Additionally, properties within 200 meters of the detection sites are treated with an organic formulation of Spinosad, which originates from naturally occurring bacteria in soil, to eliminate any mated females and reduce the density of the population.

To further reduce the population, properties within 100 meters of infested properties are subject to host-plant or fruit removal to eliminate eggs and larvae.

Furthermore, the invasive flies can then spread to other regions outside the San Francisco Bay Area.

CDFA wrote that it is working collaboratively with the United States Department of Agriculture (USDA) and the Santa Clara County Division of Agriculture on this project. This project is new and separate from the recently eradicated Medfly infestation in Alameda County, CA.

The quarantine will affect any growers, wholesalers, and retailers of susceptible fruit in the area, as well as residents. Home gardeners are urged not to move homegrown produce from their property.

However, residents living in the quarantine area may consume or process fruit on the property where they were picked or dispose of fruit by bagging and sealing it and placing it in the garbage (not green waste).  

These actions protect against the artificial spread of the infestation to nearby regions where it can affect California's food supply and backyard gardens.

The media statement confirms this eradication approach is the standard Medfly program used by CDFA and is the safest, most effective, and most efficient response program available. CDFA has successfully eradicated every detected Medfly infestation in California's history, dating back more than 40 years.

The pest is known to target more than 250 types of fruits and vegetables. Damage occurs when the female lays eggs inside the fruit. The eggs hatch into maggots, which tunnel through the flesh of the fruit, making it unfit for consumption. Residents who believe their fruits and vegetables are infested with fruit fly larvae are encouraged to call the State's toll-free Pest Hotline at 1-800-491-1899 or email [email protected].

Residents with questions about the project may call CDFA's Pest Hotline at 1-800-491-1899. To learn more about invasive species and how to protect California's fruits and vegetables, please visit www.cdfa.ca.gov/plant/fruitfly.

Aug 22, 2025 • 6:56 pm CDT
by Pete Linforth

When Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) was founded in 2016, the early-stage antibiotic pipeline was stalled.

Since its inception, CARB-X has supported 115 R&D projects in 14 countries, and CARB-X product developers have made significant progress.

Recently, CARB-X awarded Baxiva AG $3 million to develop its multivalent glycoconjugate vaccine to prevent extraintestinal pathogenic Escherichia coli (ExPEC) infections.

Baxiva's proprietary conjugation platform streamlines the development of multivalent vaccines targeting the serotype-specific polysaccharides of Gram-negative bacteria, including capsule and O antigens.

The multivalent vaccine targets the most common serotypes associated with invasive ExPEC infections.

Multivalent vaccines are designed to prevent infections caused by multiple strains or types of a single pathogen. The glycoconjugate formulation combines polysaccharide (sugar) from a pathogen's surface with a carrier protein to enhance immune response and therefore the effectiveness of the vaccine.

Escherichia coli is the leading cause of urinary tract infections, a frequent cause of neonatal sepsis, and is among the leading causes of antimicrobial resistance-associated deaths globally.

"Vaccines are a powerful tool in the global effort to prevent infections and curb the spread of antimicrobial resistance," said Erin Duffy, PhD, R&D Chief of CARB-X, in a press release on August 21, 2025.

"Baxiva's multivalent glycoconjugate vaccine project explores a range of novel polysaccharide antigens in vaccine candidate solutions, addressing a critical unmet need in infection prevention."

"We are excited to welcome Baxiva into the CARB-X portfolio and support the advancement of their platform."

The E. coli bacteria cause most urinary tract infections (UTIs).

As of August 2025, UTI vaccines are unavailable in the United States.

Aug 22, 2025 • 10:22 am CDT
Google Maps 2025

Since 2016, there has been an increase in the number of hepatitis A cases, primarily affecting men in low-endemic countries across Europe.

According to a recent report from the European Centre for Disease Prevention and Control (ECDC), Austria, Czechia, Hungary, and Slovakia reported higher-than-expected numbers of hepatitis A virus (HAV) subgenotype IB cases in 2025.

Additionally, France recently reported HAV cases, with 73 reported in the Rhône department as of August 19, 2025.

This French health ministry HAV data marks a 356% increase in cases compared to the same period in 2024.

The Rhône department is located in the east-central administrative region of Auvergne-Rhône-Alpes, which includes the Lyon Metropolis, and has a population of approximately 1,875,747.

Previous HAV outbreaks in France, particularly in the Seine-Maritime department, are reported by the ECDC.

Since HepA is a vaccine-preventable disease, the U.S. CDC recommends hepatitis A vaccination for most international travelers engaging in higher-risk activities, such as visiting smaller cities, villages, or rural areas where they may be exposed to food or water contamination.

And for travelers who plan on eating street food in France.

In the United States, HepA vaccines are generally offered at travel pharmacies and clinics in 2025.

 

 

Aug 22, 2025 • 9:32 am CDT
Maps Aug. 22, 2025

In June 2025, the World Health Organization (WHO) renewed its global alert regarding the poliovirus emergency, highlighting several countries facing significant health risks.

According to a WHO Disease Outbreak News published on August 20, 205, Israel is confronting an unquantified health risk that has been detected in Jerusalem and the Central Region.

On August 4, 2025, Israel notified WHO of a circulating vaccine-derived poliovirus type 1 (cVDPV1) outbreak.

Between February and July 2025, nine genetically linked virus isolates were found in environmental samples from seven sites. However, no human cases of paralytic polio have been reported.

Vaccine-derived poliovirus is a well-documented strain of poliovirus mutated from the strain contained initially in oral polio vaccines.

The WHO stated Israel discontinued routine use of the bivalent oral polio vaccine in March 2025 but continues to administer four doses of inactivated polio vaccine (IPV) as part of the routine immunization schedule up to 12 months of age.

The WHO/UNICEF Estimates of National Immunization Coverage for three doses of IPV in 2024 were 98%.

Unfortunately, polio vaccination coverage in Jerusalem is notably lower and below the WHO's recommended coverage threshold, which is necessary to maintain sufficient population immunity and prevent poliovirus transmission between people.

The WHO currently assesses the risk of international spread associated with this cVDPV1 detection as low due to high overall population immunity, robust poliovirus surveillance, and response capacity.

To alert international travelers visiting Israel, the U.S. CDC's updated Level 2 - Practice Enhanced Precautions, Travel Health Advisory, includes Israel.

The CDC writes, 'Before travel to any destination listed, adults who previously completed the routine polio vaccine series may receive a single, lifetime booster dose of polio vaccine.'

In the United States, the IPV polio vaccine is offered at travel clinics and pharmacies in 2025.

Aug 22, 2025 • 8:59 am CDT
US Government Aug. 21, 2025

The European Union (EU) and the United States government have announced the details of a Framework on an Agreement on Reciprocal, Fair, and Balanced Trade (Framework Agreement), which includes pharmaceutical products such as vaccines.

The mutual agreement includes 15% tariffs on EU exports to the United States. 

The August 21, 2025, statement confirmed that the U.S. and the EU, in line with their relevant internal procedures, will promptly document the Framework Agreement, which should reveal which EU-produced vaccines are subject to this tariff, which may impact the cost to consumers in the U.S. 

This pending vaccine list may include high-demand travel vaccines for chikungunya, cholera, and Japanese Encephalitis.  

 

Aug 21, 2025 • 2:49 pm CDT
Public Health France Aug. 21, 2025

Since the beginning of 2025, the European Centre for Disease Prevention and Control (ECDC) has reported West Nile virus infections in eight countries: Bulgaria, France, Greece, Hungary, Italy, Romania, Serbia, and Spain.

Case numbers reported so far this year are slightly above the average for the past decade, says the ECDC.

However, these figures remain lower than those seen in 2024 and 2018 when West Nile virus (WNV) circulation was particularly intense, with 382 and 385 cases reported by this point in the year, respectively.

While the geographical distribution has been centered in northern Italy, the ECDC's data is now indicating the southern coast of France has become an outbreak zone.

As of August 19, 2025, 13 human cases of vector-borne West Nile virus infection have been identified in six departments of mainland France.

The affected regions are PACA, Occitanie, Corsica, and, for the first time, Île-de-France.

As the summer holiday season ends in 2025, the hospitalisation rate has been notably high, with 100% of reported cases requiring hospitalization this year, compared to 93% over the past decade, according to the ECDC.

The case fatality rate so far this year stands at 7%, which is similar to the 11% observed in the previous decade.

Additionally, neurological manifestations have been reported in 56% of cases this year, compared to 66% in the past decade. Generally, cases with more severe symptoms are more likely to be diagnosed, leading to an expectation of a dominance of neurological cases.

As of August 21, 2025, the U.S. CDC's Travel Health Advisory for France does not identify WNV as a risk.

Both the ECDC and other health agencies recommend avoiding mosquito bites as the best strategy to reduce this health risk, as there are currently no approved vaccines available.

Aug 21, 2025 • 12:29 pm CDT
ISS August 21, 2025

Europe is experiencing a record number of outbreaks of mosquito-borne illnesses in 2025, including chikungunya.

New data published today by the Italian Istituto Superiore di Sanità (ISS) indicates that the country's fight against chikungunya fever continued throughout the early weeks of August 2025.

On August 21, 2025, ISS reported four local transmission events of the chikungunya virus had been identified in the northern regions of Emilia-Romagna and Veneto in two outbreaks.

Chikungunya is a viral disease transmitted to people by virus-carrying mosquitoes, often found in these regions' altitudes, through November each year.

From January to August 19, 2025, Italy's national surveillance system has recorded 66 confirmed cases of chikungunya (37 travel-associated cases and 29 indigenous (local) cases, and no related deaths, with a median age of 53 years.

From a prevention perspective, the U.S. CDC recommends either of the two approved chikungunya vaccines for international travelers visiting outbreak zones in 2025.

These vaccines, and other travel vaccines, are commercially offered at certified clinics and pharmacies in the United States.

Aug 20, 2025 • 10:56 am CDT
US Dept of State Aug. 20, 2025

As of mid-2025, the Philippines has recorded over 123,000 dengue cases nationwide from January to June, and at least 437 dengue-related deaths, with the majority occurring among children.

While the Philippines Department of Health (DOH) considers the situation manageable, as of August 20, 2025, the data reflects a 7% increase. 

In Lapu-Lapu City, Cebu, dengue cases surged by 35% compared to the same period last year. Dr. Vincent Jess Montejo of the City Health Office assured the public that the situation is not alarming.

"It's not an immediate health problem that we should be concerned about… not panic-level," Dr. Montejo said in a Facebook post.

The DOH says the case increase rate has prompted intensified vector control and public awareness campaigns.

Although there is a second-generation dengue vaccine available in numerious countries, the Philippine FDA has not yet approved it, nor the U.S. FDA.

To alert international travelers of this severe health risk, the U.S. CDC included the Philippines in its recent Level 1 Travel Health Advisory.

Aug 20, 2025 • 8:25 am CDT
USDA 2025

The U.S. Department of Health and Human Services recently issued a declaration that allows the U.S. Food and Drug Administration (FDA) to issue Emergency Use Authorizations for animal drugs to treat or prevent infestations caused by the New World Screwworm (NWS).

As of August 20, 2025, there are no FDA-approved drugs for NWS, nor are there vaccines authorized to protect people in the United States.

As of today, NWS infestations have been confirmed in Central America and Mexico, but not in Texas.

The FDA stated in a press release that the parasite's risk to human health in the United States remains very low. Still, the potential future threat to animal populations and the food supply chain requires proactive action. 

“Our priority is to safeguard both animal health and the nation’s food supply,” said FDA Commissioner Marty Makary, M.D., M.P.H., in a press release.

“FDA is acting swiftly and responsibly to help ensure we have the necessary tools to prevent and control New World Screwworm, minimizing risks to agriculture and public health.”

Over the last two months, about $900 million has been committed by the U.S. government to combat the NWS from reaching the U.S.

NWS infests warm-blooded animals, including livestock, pets, wildlife, and, in rare cases, humans, causing severe tissue damage and sometimes death, writes the FDA.

Aug 20, 2025 • 5:33 am CDT
Maps 2025

The Florida Department of Health in Hillsborough County (DOH Hillsborough) recently informed residents of a confirmed human case of locally-acquired dengue fever.

According to data published by the state (Week 33) on August 19, 2025, this is the 14th local dengue case reported in 2025. Previous dengue cases have been confirmed in the east coast near Melbourne (11) and Miami (2).

DOH-Hillsborough and Hillsborough County Mosquito Control stated in a media release that they are coordinating surveillance and prevention efforts by conducting aerial spraying to reduce the spread of this mosquito-transmitted virus to other people.

This area of Florida includes cities such as Tampa and has a local population of over 1.4 million.

Additionally, Florida has reported 154 dengue cases among international travelers, many of whom had recently visited Cuba.

As of August 20, 2025, dengue vaccines are not offered in Florida.

Aug 19, 2025 • 2:37 pm CDT
Google Maps August 19, 2025

The World Health Organization (WHO) recently announced that the Federal Democratic Republic of Nepal, a country located high in the Himalaya Mountains in southeast Asia, has eliminated rubella as a public health problem.

Rubella, or German measles, is a vaccine-preventable disease that is a highly contagious viral infection. It is severe for pregnant women as infection can lead to a range of lifelong and debilitating congenital disabilities, says the WHO.

"Nepal's success reflects the unwavering commitment of its leadership, persistent efforts of the health care workers and volunteers, and unstinting support of engaged and informed communities, for a healthy start for babies and a future free of rubella disease," said Dr Catharina Boehme, Officer-In-Charge WHO Southeast Asia, in a press release on August 18, 2025.

Unfortunately, this disease eradication success has not translated to the Japanese Encephalitis (JE), a flavivirus transmitted by mosquitoes that is often contracted from infected pigs and sheep.

As of August 2025, JE infections are the leading cause of viral encephalitis in 24 countries in the WHO Southeast Asia and Western Pacific/Oceania Regions, exposing more than 3 billion people to infection risks.

In Nepal, Japanese Encephalitis has been a significant public health concern since 1978, especially in the Terai region, an area that borders India.

JE is also a vaccine-preventable disease. The WHO indicated in August 2025 that Nepal's national JE vaccination coverage surpasses 95%. The government integrated JY vaccinations beginning in 2015.

However, as of August 19, 2025, the Health Ministry's data show 33 JE cases and three fatalities this year.

In 2024, 23 people died, and 80 others were infected with the JE virus.

Traditionally, JE vaccination hasn't been routinely recommended for short-term travelers to Nepal.

The WHO and the U.S. CDC recommend that international travelers visiting Nepal consider vaccination. Proven JE vaccines are available in the United States, commercially offered at various travel clinics and pharmacies in 2025.

Aug 19, 2025 • 9:27 am CDT
International Vaccine Access Center Aug. 2025

The Pan American Health Organization (PAHO) recently urged countries in the Americas to strengthen immunization activities as measles cases continue to rise in the region.

As of August 8, 2025, a total of 10,139 confirmed measles cases and 18 related deaths have been reported across ten countries, representing a 34-fold increase compared to the same period in 2024.

Countries with the highest case numbers include Canada (4,548 cases), Mexico (3,911 cases), and the United States (1,356 cases).

In Mexico, most deaths have occurred in indigenous people between 1 and 54 years of age.

However, in the U.S., the state of Texas recently declared its measles outbreak had ended.

The current outbreaks are associated with two genotypes of the measles virus and linked to low vaccination coverage, with 71% of cases occurring in unvaccinated individuals.

One genotype has been identified in outbreaks across eight countries, particularly among Mennonite communities in Canada, the United States, Mexico, Belize, Argentina, Bolivia, Brazil, and Paraguay. 

In 2024, coverage with the first dose of the measles, mumps, and rubella (MMR) vaccine in the region reached 89% (two percentage points higher than in 2023), while the second dose increased from 76% to 79%.

"Measles is preventable with two doses of a vaccine, which is proven to be very safe and effective. To stop these outbreaks, countries must urgently strengthen routine immunization and conduct targeted vaccination campaigns in high-risk communities," said Dr. Daniel Salas, Executive Manager of the Special Program for Comprehensive Immunization at PAHO, in a press release on August 15, 2025.

Worldwide, measles cases continue to be reported in numerious countries in 2025. To alert international travelers, the U.S. CDC published a Level 1 Travel Health Advisory in May, recommending MMR vaccination before visiting outbreak areas.

Aug 19, 2025 • 4:28 am CDT
US CDC Aug. 2025

Before 2006, chikungunya fever infections were rarely identified in the United States. However, starting in 2014, cases of chikungunya began to appear among U.S. travelers returning from affected regions in the Americas.

Local transmission of the virus has since been documented in Florida, Texas, Puerto Rico, and the U.S. Virgin Islands.

As of August 19, 2025, there have been 50 reported travel-related cases in the U.S.

Last year, 199 cases were confirmed.

The U.S. Centers for Disease Control and Prevention (CDC) has highlighted several countries where travelers are acquiring this mosquito-borne disease.

The CDC has issued a chikungunya travel health notice for outbreaks in Bolivia, China, Kenya, Madagascar, Mauritius, France, the Department of Mayotte and Réunion, Somalia, and Sri Lanka.

According to the Pan American Health Organization (PAHO), Brazil is leading all countries in the region with over 204,000 cases in 2025.

The CDC recently wrote that international travelers can protect themselves by preventing mosquito bites. And, if you are pregnant, you should reconsider travel to the affected areas, particularly if you are close to delivering your baby.

"The CDC recommends chikungunya vaccination for travelers going to areas with current outbreaks, and also for people traveling to regions or countries with elevated risk—particularly if they'll be staying for six months or longer," Jeri Beales, MSN, RN, BS, informed Vax-Before-Travel. 

"This is especially true for individuals who are older and have chronic conditions like diabetes." 

"The list of countries and regions with ongoing outbreaks and elevated risks changes frequently, so be sure to seek advice from a travel clinic or physician's office that specializes in travel health before your trip," added Beales, with Destination Health Travel Clinic in the greater Boston, MA area.

Currently, two chikungunya vaccines are approved for use and commercailly in the U.S. at certified travel clinics and pharmacies.

Aug 18, 2025 • 3:53 pm CDT
Google Maps August 18, 2025

As summer draws to a close in August 2025, millions of beachgoers flock to New Jersey's extensive coastline. While many vacationers enjoy the waves and surfing at the shore, this year, mosquito bites may become a popular topic of conversation.

According to news posted today, the New Jersey Departments of Health (NJDOH) and Environmental Protection are investigating a case of malaria in a resident of Morris County with no international travel history.

NJDOH wrote on August 18, 2025, that it is possible the resident was infected by a virus-carrying mosquito with malaria in New Jersey.

If confirmed, this would be the first known locally acquired case of malaria in New Jersey since 1991.

"While risk to the general public is low, it's important to take the necessary precautions to prevent locally acquired malaria in New Jersey. The most effective ways are to prevent mosquito bites in the first place and to ensure early diagnosis and treatment of malaria in returning travelers,” said Acting Health Commissioner Jeff Brown, in a press release."

“Anyone traveling to countries with widespread malaria should take appropriate steps to prevent malaria while traveling and monitor for symptoms.”

Malaria is a mosquito-borne disease caused by a parasite transmitted by certain mosquitoes and is widespread in many tropical and subtropical countries.

For example, the state of Florida has reported numerious travel-related malaria cases involving travelers visiting Cuba in 2025.

While approved for use in Africa, malaria vaccines are currently unavailable in the United States.