Oropouche Outbreak Travel Advisory Updated

The US Centers for Disease Control and Prevention (CDC) updated its Level 1, Practice Usual Precautions, Travel Health Advisory regarding the ongoing spread of the Oropouche virus in the Region of the Americas.

As of September 18, 2025, the CDC is reporting cases of Oropouche in Brazil, Cuba, Panama, and Peru.

For example, the Panama Ministry of Health reported that 10 human cases of locally acquired Oropouche virus disease had been detected in various districts of the Veraguas region, including Santiago, La Pena, Atalaya, and Rodrigo Luque.

Between January and the end of July 2025, about 501 cases, including one death, were reported in Panama by the Pan American Health Organization.

In the United States, states such as Florida reported 103 cases of Oropouche fever in 2024 in people who traveled to Cuba. The Florida counties reporting cases were led by Miami-Dade (61).

The CDC states that travelers to affected areas should take steps to prevent bug bites, infected midges, and mosquitoes.

This virus can also be transmitted from a pregnant woman to her fetus. Recent scientific reports have found evidence of Oropouche virus and viral RNA in patients' bodily fluids, including semen and vaginal fluids.

Currently, there are no Oropouche vaccines available for disease prevention in 2025.