Oropouche Virus Travel Advisory Reissued for the Americas

Since the summer of 2024, countries in the Region of the Americas have reported low numbers of Oropouche cases. In the past, Oropouche virus has caused periodic outbreaks in and around the Amazon Basin.

According to the U.S. Centers for Disease Control and Prevention (CDC), the countries most impacted include Brazil, Cuba, Panama (specifically, the Darién Province), and Peru.

Furthermore, countries such as Spain have reported Oropouche cases in travelers to the Americas in 2025.

The disease is primarily spread through bites from infected midges and mosquitoes.

The CDC's updated Travel Health Advisory says travelers visiting affected areas should take steps to prevent bug bites and consider using condoms or not having sex during travel and for six weeks after returning from travel.

As of July 14, 2025, the CDC stated the Oropouche virus has been found in semen, but it is unknown if it can be spread through sex.

Currently, there is no preventive vaccine available.