Mexico Reported Only Four Zika Cases in 2025

While the Zika virus (ZIKV) has faded mainly from global headlines since the major outbreaks of 2015-2016, low-level transmission of this mosquito-borne and sexually transmitted virus continues in parts of Mexico, according to recent data from health authorities.

As of January 11, 2026, the Pan American Health Organization (PAHO) and Mexico's National Epidemiological Surveillance System report that Mexico confirmed 30 autochthonous (locally acquired) Zika cases in 2024, with only four additional cases reported in 2025.

The three Mexican states with the highest number of ZIKV-positive cases during that outbreak were Veracruz, Nuevo León, and Yucatán. These areas, particularly in coastal and lowland regions, remain at-risk for millions of visitors each year due to the presence of Aedes mosquitoes.

A study published in October 2025 analyzed data from the 2016-2018 outbreak period in Mexico, reviewing 13,259 suspected ZIKV cases tested by RT-qPCR from August 2016 to January 2018. Of these cases, 10.7% (1,419) tested positive for Zika virus disease (ZVD).

Notably, 25% (3,313) of the ZIKV-positive cases were in pregnant women, highlighting the ongoing risk to maternal and fetal health during periods of higher virus circulation.

The PAHO and the U.S. Centers for Disease Control and Prevention (CDC) say ZIKV infection during pregnancy can lead to serious complications, such as congenital Zika syndrome, which includes microcephaly and other congenital disabilities.

The CDC classifies Mexico as having current or past Zika transmission and ZVD, which indicates a potential risk.

However, as of January 11, 2026, no CDC Travel Health Notice for Zika is in effect for Mexico. The CDC has shifted away from blanket recommendations against travel for pregnant women to Mexico but continues to advise caution.

These health agencies advise travelers, especially pregnant women or those planning pregnancy, to take strict measures to prevent mosquito bites when visiting at-risk areas such as Mexico.

Although there is currently no Zika vaccine available, clinical research continues.

Recent data from PAHO dashboards indicate that sporadic Zika confirmations have been reported in Brazil, Bolivia, Colombia, Costa Rica, El Salvador, Guatemala, and Peru.