LA County Confirms First West Nile Virus Fatality of 2025

The Los Angeles County Department of Public Health (LACDPH) recently confirmed the first local death from the West Nile virus (WNV) in the 2025. The resident of the San Fernando Valley was hospitalized and died from a neurological illness caused by severe West Nile virus.

A total of 14 West Nile virus infections have been documented in Los Angeles County in 2025, excluding Long Beach and Pasadena. Half of the infected people live in the San Fernando Valley region.

Public Health reports West Nile virus cases every year, generally from June to November, as the virus is endemic in the region.

According to LACDPH, about 1 in 150 people will have severe WNV symptoms that may include high fever, stiff neck, muscle weakness, and sometimes rash. Symptoms usually appear 3 to 14 days after being infected.

West Nile virus is the most common mosquito-borne disease affecting residents of LA County, which has also reported locally acquired dengue cases in 2025.

"To the family and friends grieving the loss of a loved one due to West Nile virus, we extend our heartfelt condolences,” said Muntu Davis, MD, MPH, Los Angeles County Health Officer, in a press release on October 24, 2025.

“This tragic loss reminds us how dangerous mosquito-borne diseases like West Nile virus and dengue can be. Protect yourself and your neighbors by using insect repellent, getting rid of standing water where mosquitoes breed, and keeping window and door screens in good repair. Small actions like these can make a big difference in preventing illness.”

In collaboration with local vector control agencies, Public Health monitors the risk of WNV infection. It actively engages residents to provide information about reducing the risk by promoting protective measures against mosquitoes.

As of October 27, 2025, there is no WNV vaccine available in the USA.