8% More Typhoid Cases Confirmed in the U.K.

The latest data published by the UK Health Security Agency (UKHSA) shows an increase in travel-associated enteric fever cases, specifically typhoid and paratyphoid fever, serious but preventable illnesses caused by Salmonella bacteria.

In 2024, there were 702 reported cases in England, Wales, and Northern Ireland, representing an 8% rise from the 645 cases recorded in 2023.

This number marks the highest annual total of cases ever.

In the UK, most cases of enteric fever are contracted abroad, particularly in regions with poor hygiene and sanitation. Previous surveillance has indicated a troubling increase in antibiotic-resistant typhoid strains in Pakistan, which diminishes the effectiveness of commonly used antibiotics and complicates treatment.

As of June 14, 2025, a free typhoid vaccination is available in the UK for some travelers; however, there is currently no vaccine for paratyphoid fever.

The UK's Travel Health Pro website says, 'Ideally, travellers should consult their GP, practice nurse, pharmacist, or travel clinic at least 4 to 6 weeks before their trip for individual advice, travel vaccines, if relevant for their destination.

In the United States, the CDC estimates that 5,700 of cases of typhoid fever occur in the United States each year. Almost all cases occur among international travelers returning from South Asia, primarily Bangladesh, India, and Pakistan.

The CDC says vaccination can help prevent typhoid fever. Two typhoid vaccines are available in the United States: an oral vaccine and an injectable vaccine.

Bavarian Nordic's Vivotif® (Ty21a) is the only oral typhoid vaccine licensed by the U.S. Food and Drug Administration.

Find out if you need a typhoid vaccine at www.cdc.gov/travel. Or visit a local travel vaccine clinic or pharmacy.