Local Mpox Case Confirmed In Madrid

According to Spanish media, a man residing in the Community of Madrid is the first Mpox clade 1b case of autochthonous (local) infection of the most contagious strain of the sexually transmitted virus.

The Madrid Directorate General of Public Health announced in late September 2025 that the patient is in home isolation and is progressing favorably. His close contacts are being investigated to identify potential secondary cases.

As of early October 2025, all reported cases of this Mpox variant in Europe had been imported, primarily from African countries.

According to the latest epidemiological bulletin from the Carlos III Health Institute, since 2022, Spain has detected a total of 9,027 cases of Mpox, 487 of them this year.

The U.S. CDC states that Mpox is a vaccine-preventable disease, with various vaccines approved for human use and commercailly available at select pharmacies.