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Over the last few decades, the Advisory Committee on Immunization Practices (ACIP) of the U.S. Centers for Disease Control and Prevention (CDC) has issued recommendations on vaccine use for the civilian population of the United States.

According to the draft agenda for the ACIP meeting posted on December 1, 2025, this Thursday's topics will include updates from the CDC, specifically regarding the Hepatitis B vaccine.

The ACIP includes up to 19 voting members who make vaccine recommendations selected by the Secretary of the U.S. Department of Health and Human Services.

The CDC says, 'The best way to prevent hepatitis B is by getting vaccinated.'

Then, on December 5, 2025, presentations of the ACIP Workgroups, CDC Vaccine Risk Monitoring Evaluation, Vaccine Schedule History, Childhood/Adolescent Immunization Schedule Discussion and Considerations.

Previous ACIP meeting agendas and presentations are posted on this CDC webpage.

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Ebola vaccines are approved in 2025
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Recently, the World Health Organization stated that available data indicate that during 2024 and 2025, poliovirus has spread geographically alongside continued transmission within core reservoir areas in both polio-endemic countries.

To highlight this severe health risk, the U.S. CDC updated its Level 2 - Practice Enhanced Precautions notice, which now identifies 32 countries. 

This list includes Germany, Israel, and the United Kingdom.

The CDC statement issued on November 25, 2025, says that before traveling to any destination listed, adults who previously completed the entire routine polio vaccine series may receive a single, lifetime booster dose of polio vaccine.

When departing from the USA, polio vaccination services are offered at travel clinics and pharmacies.

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The U.S. Centers for Disease Control and Prevention (CDC) recently issued a Travel Health Notice regarding the expanding health risk of contracting the rabies virus when visiting India. And the CDC reaffirmed the risk of fake rabies vaccinations.

On November 25, 2025, the CDC posted a Level 1 - Practice Usual Precautions notice stating a case of Rabies had been reported in the U.S. in a traveler from India. Travelers potentially exposed to Rabies in India should immediately seek local medical care.

This advice is essential as Rabies is a viral disease that affects the central nervous system. Last year, India's National Centre for Disease Control recorded 54 suspected rabies deaths.

The CDC says upon returning home, travelers should follow up with their health care provider as soon as possible. And in the USA, infected bats are the leading source of infection in people.

To prevent contracting rabies, travelers to India should avoid all contact with dogs, cats, and other wild mammals.

And consider getting vaccinated against Rabies before traveling abroad.

In the United States, rabies vaccines are available at pharmacies and travel clinics.

In India, the circulation of counterfeit ABHAYRAB human rabies vaccine has recently been reported in major cities. Counterfeit vaccines may not be effective in the prevention of Rabies and could contain harmful ingredients, says the CDC.

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Valneva SE today announced positive final results regarding the immunogenicity and safety from its Phase 2 study, VLA15-221, of the Lyme disease vaccine candidate, VLA15.

According to Valneva's press release on November 26, 2025, this study's findings demonstrated a strong anamnestic immune response and a favorable safety profile six months after the third booster dose (at month 48) across all age groups.

Furthermore, these results confirm that the vaccine is compatible with the expected benefits of annual vaccination before the start of each Lyme season, which coincides with increased outdoor activities in the Northeast and Midwest regions of the United States.

Juan Carlos Jaramillo, M.D., Chief Medical Officer of Valneva, commented in a press release. "Lyme disease continues to expand geographically and remains a pressing unmet medical need affecting communities across the Northern Hemisphere."

"Each set of positive results moves us closer to the possibility of making this vaccine available to adults, adolescents, and children living in Lyme-endemic areas."

This is very encouraging news as there are currently no approved human vaccines for Lyme disease, and VLA15 has advanced the furthest in clinical development.

Valneva partnered with Pfizer Inc. in April 2020 to develop and commercialize VLA15.

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Launched in early November 2025, the Walgreens Acute Respiratory Index (ARI) for 2025-2026 tracks influenza and COVID-19 hotspots using prescription, testing, and over-the-counter product purchase data from its locations nationwide.

As of November 22, 2025, the District of Columbia, New York, Texas, and Michigan lead Walgreens' ARI index.

Nationwide, the overall ARI score was 2.5 out of 5.0.

Walgreens' unique digital tool offers a more comprehensive view of respiratory illness trends across the U.S., enabling the public, healthcare providers, and health officials to make more informed decisions throughout the respiratory virus season.

Rick Gates, Walgreens' chief pharmacy officer, commented in a press release, "Vaccination remains the safest and most effective way to prevent highly contagious illnesses like flu, RSV, and COVID-19."

Previously, the U.S. CDC FluView for Week 47 will be posted on November 21, 2025, stating 'seasonal influenza activity in the United States remains low nationally but is increasing.'

Various flu shots are offered throughout the influenza season at most community pharmacies.

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Walgreens Respiratory Illness Index November 22, 2025
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On the occasion of the Jubilee of the Poor, a special holy year which occurs once every 25 years, the European Centre for Disease Prevention and Control (ECDC) has been conducting enhanced monitoring through its epidemic intelligence activities. 

With multiple events that take place throughout the year and nning until December 2025, it is estimated that more than 35 million pilgrims will visit Rome during the Jubilee of the Poor.

As of November 21, 2025, the ECDC says the probability of EU/EEA citizens becoming infected with communicable diseases during the Jubilee 2025 is low if general preventive measures are followed, such as influenza vaccination according to national immunisation schedules.

 

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Japanese Encephalitis Vaccine offered in the USA in 2025
Malaria Vaccines offered in 24 African countries in 2025
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The Washington State Department of Health (WDOH) recently confirmed the death of an older adult from Grays Harbor County related to a specific type of 'bird flu.' The individual had underlying health conditions and was receiving treatment for an infection of the H5N5 avian influenza virus.

This report from WDOH, issued on November 21, 2025, marks the first human case of avian influenza A (H5N5) reported worldwide.

Washington Governor Bob Ferguson stated in a Facebook post, "My condolences to this individual's family and loved ones. Thank you to the dedicated medical professionals who cared for them, and to the public health experts working to monitor the situation and educate the public."

This person had a backyard flock of mixed domestic birds. DOH sampling identified avian influenza virus in the environment of the flock, making exposure to the domestic poultry, their environment, or wild birds the most likely source of exposure for this patient. People who had exposure to the backyard flock and its environment are also being monitored by local health authorities for symptoms.

The WDOG says the risk to the public remains low as no other people involved have tested positive for avian influenza.

Public health officials will continue to monitor anyone who was in close contact with the patient for symptoms to ensure that human-to-human spread has not occurred. There is no evidence of transmission of this virus between people.

From a prevention perspective, at least 20 H5 influenza vaccines are licensed worldwide.

As of November 25, 2025, U.S. FDA-approved avian influenza vaccines are not commercially available in the USA.

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