Dominican Republic Travel Vaccines 2026

Dominican Republic Travel Vaccines March 2026

The Dominican Republic is situated on the eastern part of the island of Hispaniola in the Caribbean Sea, sharing a maritime border with Puerto Rico. As of 2026, the U.S. Centers for Disease Control and Prevention (CDC), Australia, and the UK Travel Health Pro publish Travel Health Notices regarding current health issues in the Dominican Republic. No vaccinations are required if arriving from the United States. 

The U.S. Department of State issued a Level 2 - Exercise increased caution Travel Advisory for the Dominican Republic in 2025. Visitors should exercise increased caution in the DR due to civil unrest. A visa is required for stays exceeding 30 days. A U.S. passport must be valid for at least 6 months from the date of arrival in the DR. Enroll in the Smart Traveler Enrollment Program (STEP) to receive digital alerts. 

Chikungunya Dominican Republic

The DR has reported chikungunya cases in the past and shares a land border with Haiti, which has reported cases in 2025.

Dengue Dominican Republic

The Ministry of Health has implemented various actions as part of the National Dengue Plan to reduce the incidence of dengue, including the relaunch of the "eliminate, clean, and cover" campaign. For Epidemiological Week 33, 2025, one confirmed case of dengue was reported, bringing the total for the year to 174. According to data from the Epidemiology Directorate, 1,110 dengue cases were recorded in the same period in 2024, reflecting a reduction of more than 85%.

Leptospirosis Dominican Republic 

The Dominican Republic's Ministry of Public Health reported a notable decrease in leptospirosis cases during early 2026 compared to the same period last year. In 2025, the DR reported a total of 186 confirmed cases of leptospirosis, which included 19 deaths. This data represented a significant 275% increase in incidence compared to the 48 cases reported in 2024. The most Affected Areas were Santo Domingo, La Altagracia, Santiago, Puerto Plata, and Duarte.

Malaria Dominican Republic

In early 2026, 17 malaria cases were reported. The Epidemiology Department reports a total of 737 confirmed malaria cases have been reported to the National Epidemiological Surveillance System as of late August 2025. As of May 2025, 70% of the confirmed cases are from San Juan. The UK advises travellers to take antimalarials if appropriate for the area they are visiting. Malaria vaccines are unavailable in the DR; however, antimalarial producers are offered.

Oropouche Dominican Republic

As of September 2025, an outbreak of Oropouche virus disease is ongoing in the DR.

Urinary Tract Infection (UTI) Vaccine Dominican Republic

In the Dominican Republic, the local UTI vaccine contact is available at this link.